杨新健

一、 个人简介

杨新健，中国科学院长春应用化学研究所博士（2007.09-2013.01），新加坡国立大学博士后（2013.04-2015.03），现为教授，博士研究生导师。迄今为止，发表SCI收录论文40余篇；先后主持了国家自然科学基金、河北省自然科学基金等课题。

邮箱： jianxinyang123@163.com

二、 主讲课程及研究方向

主讲课程：

分析化学；基础化学分析实验

研究方向：

生物医用材料的合成及应用

三、 代表性论文

1. Lingzhi Cao, Xinjian Yang,* Yimei Li, Yang Yang, Qiulin Liu, Massimo Bottini, Yi Jin, * Bei Wang, Jinchao Zhang,* and Xing-jie Liang*. Near-Infrared Light-Activatable DNA Tentacles for Efficient Inhibition of Tumor Metastasis by Bio-Orthogonal Cell Assembly. ACS nano, 2024, 18, 18046−18057.

2. Jingjing Li, Xin Gao, Shaochun Li, Xinyu Zhang, Jiamin Guo, Bei Wang, Yi Jin, Jinchao Zhang, Xinjian Yang* and Enjun Wang*. Wound microenvironment self-adaptive all-in-one hydrogel for rapid healing of the diabetic wound. J. Mater. Chem. B, 2024, 12, 2070.

3. Han Zhu#, Xin Gao#, Bei Wang, Biao Niu, Dandan Liu, Jinchao Zhang, Yi Jin*, Xinjian Yang* A biodegradable hollow nanoagent enables a boosted chemodynamic therapy by simultaneous autophagy inhibition and macrophage reeducation. Int. J. Pharm. 2023, 643, 123248.

4. Xin Gao, Bei Wang, Jingjing Li, Biao Niu, Lingzhi Cao, Xing-jie Liang, Jinchao Zhang,*Yi Jin,* and Xinjian Yang*. Catalytic Tunable Black Phosphorus/Ceria Nanozyme: A Versatile Oxidation Cycle Accelerator for Alleviating Cisplatin-Induced Acute Kidney Injury. Adv. Healthcare Mater. 2023, 2301691.

5. Dandan Han, Xing Zhang, Yichuan Ma, Xinjian Yang*, Zhenhua Li*. The development of live microorganism-based oxygen shuttles for enhanced hypoxic tumor therapy. Materials Today Bio, 2003, 18, 100517.

6. Wendi Huo, Xinjian Yang*, Bei Wang, Lingzhi Cao, Ziyuan Fang, Zhenhua Li, Huifang Liu, Xing-jie Liang, Jinchao Zhang*, Yi Jin*. Biomineralized hydrogel DC vaccine for cancer immunotherapy: A boosting strategy via improving immunogenicity and reversing immune-inhibitory microenvironment. Biomaterials, 2022, 2882, 121722.

7. Linna Liang, Wendi Huo, Bei Wang, Lingzhi Cao, Haoran Huo, Yixin Liu, Yi Jin*, Xinjian Yang*, DNAzyme-Based nanoflowers for reversing P-glycoprotein-mediated multidrug resistance in breast cancer. J. Colloid Interf. Sci., 2022, 608, 2985–2993.

8. Feng Wang, Yi Jin*, Xin Gao, Haoran Huo, Bei Wang, Biao Niu, Zihan Xia, Jinchao Zhang*, Xinjian Yang*. DNAzyme-assisted bioconstruction of logically activatable nanoplatforms for enhanced cancer therapy. J. Colloid Interf. Sci., 2022, 623,1132–1141.

9.Hao Wang#, Yi Jin#, Yanli Tan, Han Zhu, Wendi Huo, Pei Niu, Zhenhua Li, Jinchao Zhang*, Xing-jie Liang, Xinjian Yang*. Photo-responsive hydrogel facilitates nutrition deprivation by an ambidextrous approach for preventing cancer recurrence and metastasis. Biomaterials, 2021, 275, 120992.

10. Guangshun Yu, Na Feng, Dan Zhao, Hao Wang, Yi Jin, Dandan Liu, Zhenhua Li, Xinjian Yang*, Kun Ge, Jinchao Zhang*. A highly selective and sensitive upconversion nanoprobe for monitoring hydroxyl radicals in living cells and the liver. Sci China Life Sci. 2021,64, 434–442.

四、 科研项目

1. 中央引导地方项目，246Z2702G，2024.05-2027.03

2. 河北省青年拔尖人才支持项目（第三批），2018-2024.

3. 河北省自然科学基金，B2021201005，2021.01-2023.12

4. 河北省自然科学基金（省杰青），B2018201221，2018.01-2020.12

5. 国家自然科学基金，21603051，2017.01-2019.12.